Drug-induced peripheral nerve palsy: a real-world study based on FAERS data from 2004 to the third quarter of 2024

This study identified that several medications, including bupivacaine, dalfampridine, natalizumab, minocycline, and ocrelizumab, are significantly associated with an increased risk of peripheral nerve palsy. These findings contribute to a deeper understanding of drug safety profiles, support the promotion of rational medication use, and provide valuable insights to inform clinical decision-making.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-08
DOI
https://doi.org/10.3389/fphar.2025.1691263
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
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article

Drug-induced peripheral nerve palsy: a real-world study based on FAERS data from 2004 to the third quarter of 2024

Xueliang Yi, Nengwei Yu, Yingjie Li
Frontiers in Pharmacology
Pharmacovigilance and Adverse Drug Reactions
article

Drug-induced peripheral nerve palsy: a real-world study based on FAERS data from 2004 to the third quarter of 2024

Xueliang Yi, Nengwei Yu, Yingjie Li
article en

Abstract

This study identified that several medications, including bupivacaine, dalfampridine, natalizumab, minocycline, and ocrelizumab, are significantly associated with an increased risk of peripheral nerve palsy. These findings contribute to a deeper understanding of drug safety profiles, support the promotion of rational medication use, and provide valuable insights to inform clinical decision-making.

Frontiers in PharmacologyVol. 16
University of Electronic Science and Technology of China (CN), Chengdu Medical College (CN), Chengdu University (CN)
Good health and well-being
Openalex Percentile: Top 94%
Pharmacovigilance and Adverse Drug Reactions
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