Evaluation of Three Quantification Methods for Monitoring Twelve Antiseizure Medications in Human Plasma by LC-MS/MS

The established LC-MS/MS method for the determination of antiseizure medication concentration was characterized by a simple operation procedure, short analysis time, high sensitivity, and good accuracy, providing a simple and reliable assay for the monitoring of antiseizure medication therapy.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2026-01-07
DOI
https://doi.org/10.1097/ftd.0000000000001434
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of Three Quantification Methods for Monitoring Twelve Antiseizure Medications in Human Plasma by LC-MS/MS

Shanshan Chen, Donghan Wang, Yuanyuan Zhao, Jiaqi Wang et al.
Therapeutic Drug Monitoring
Epilepsy research and treatment
article

Evaluation of Three Quantification Methods for Monitoring Twelve Antiseizure Medications in Human Plasma by LC-MS/MS

Shanshan Chen, Donghan Wang, Yuanyuan Zhao, Jiaqi Wang, Yuhang Yan, Chunhua Zhou, Qixuan Sun, Yueyao Luan, Jing Yu
article en

Abstract

The established LC-MS/MS method for the determination of antiseizure medication concentration was characterized by a simple operation procedure, short analysis time, high sensitivity, and good accuracy, providing a simple and reliable assay for the monitoring of antiseizure medication therapy.

Therapeutic Drug Monitoring
Hebei Mental Health Center (CN), First Affiliated Hospital of Hebei Medical University (CN), Hebei Science and Technology Department (CN)
Good health and well-being
Openalex Percentile: Top 93%
Epilepsy research and treatment
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