Maternal red blood cell folate metabolites were dynamically associated with neonatal amino acids and acylcarnitines in heel blood: a prospective cohort study

Although maternal total folate and 5-MTHF levels showed no significant association with neonatal metabolites, maternal certain folate metabolites, especially THF, exhibited trimester-specific associations with neonatal metabolic pathways, warranting clinical attention.

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Publication Details

Journal
Nutrition & Metabolism
Published
2026-01-07
DOI
https://doi.org/10.1186/s12986-025-01064-2
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Maternal red blood cell folate metabolites were dynamically associated with neonatal amino acids and acylcarnitines in heel blood: a prospective cohort study

Xilin Shi, Tengda Chen, Y Zhang, Yuanyuan Kong et al.
Nutrition & Metabolism
Folate and B Vitamins Research
article

Maternal red blood cell folate metabolites were dynamically associated with neonatal amino acids and acylcarnitines in heel blood: a prospective cohort study

Xilin Shi, Tengda Chen, Y Zhang, Yuanyuan Kong, Guanghui Li, Z Q Wang, Yixuan Lu, Lirui Zhang, Xin Yan, Wei Zheng, Ruihua Yang
article en

Abstract

Although maternal total folate and 5-MTHF levels showed no significant association with neonatal metabolites, maternal certain folate metabolites, especially THF, exhibited trimester-specific associations with neonatal metabolic pathways, warranting clinical attention.

Nutrition & MetabolismVol. 23(1)
Capital Medical University (CN), Beijing Obstetrics and Gynecology Hospital (CN)
Good health and well-being
Openalex Percentile: Top 95%
Folate and B Vitamins Research
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