Thyroid function and liver fibrosis: FT3 levels are inversely and independently correlated with enhanced liver fibrosis score in solid organ transplant patients with dysglycemia
In SOT recipients with dysglycemia lower FT3 levels were independently associated with increased ELF scores. This finding suggests a potential link between subtle variations in thyroid function and markers of fibrogenic activity in metabolically vulnerable transplant recipients. Prospective studies are warranted to elucidate the causal directionality of this association and its clinical relevance.
Authors
- Vitale Miceli (ORCID: https://orcid.org/0000-0001-8922-9909)
- Fabrizio Emanuele
- Rosaria Tinnirello (ORCID: https://orcid.org/0000-0002-4324-5097)
- Salvatore Gruttadauria (ORCID: https://orcid.org/0000-0002-9684-8035)
- Aldo Eugenio Calogero (ORCID: https://orcid.org/0000-0001-6950-335X)
- Alessandro Mattina (ORCID: https://orcid.org/0000-0003-3458-0894)
- Claudia Leanza
- Maria Ausilia Giusti
- Marco Calogero Amato
- Vincenzina Lo Re
- Giovanna Lo Iacono
- Antonio Galante
- Massimo Pinzani
- Gioacchin Iannolo
- Giovanni Zito
Institutions
- Università degli Studi di Enna Kore (IT)
- The Royal Free Hospital (GB)
- University of Catania (IT)
- University College London (GB)
- Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1726617
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00