Targeting fatty acid metabolism in hepatic macrophages mitigates acetaminophen-induced liver injury and promotes regeneration in mice
Our findings suggest that targeting de novo lipogenesis in hepatic macrophages may represent a novel strategy for treating AILI.
Authors
- Qian Zhu (ORCID: https://orcid.org/0000-0003-1045-8819)
- P. M. Huang (ORCID: https://orcid.org/0009-0009-7837-4217)
- Xiaoyu Chen (ORCID: https://orcid.org/0000-0001-8860-747X)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- C. Hu
- Liuyu Xie
- Beng Wu
- C. Chen
- Xiaoyong Jiang
- Hao Li
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- Shenzhen International Travel Health Care Center (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1097/hc9.0000000000000865
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00