Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7

DHRS7 is significantly downregulated in NEC tissues, potentially serving as a diagnostic marker, while its decreased expression is associated with increased neutrophil and macrophage infiltration, underscoring its vital role in immune modulation in NEC.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-06
DOI
https://doi.org/10.3389/fimmu.2025.1743878
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7

W. Ge, Qiyou Yin, Y. H. Chen, Kexin Gao et al.
Frontiers in Immunology
Infant Nutrition and Health
article

Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7

W. Ge, Qiyou Yin, Y. H. Chen, Kexin Gao, Jingjing Lu
article en

Abstract

DHRS7 is significantly downregulated in NEC tissues, potentially serving as a diagnostic marker, while its decreased expression is associated with increased neutrophil and macrophage infiltration, underscoring its vital role in immune modulation in NEC.

Frontiers in ImmunologyVol. 16
Nantong University (CN), Affiliated Hospital of Nantong University (CN)
Government of Jiangsu Province
Good health and well-being
Openalex Percentile: Top 95%
Infant Nutrition and Health
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