Study on Preparation and Antibacterial Property of DOMA-SBMA Copolymer Coatings on Stainless Steel Surfaces

A combination of surface wettability and antibacterial performance is highly imperative for construction of antibacterial coatings. In this study, motivated by the antibacterial properties of zwitterionic polymer, mussel-inspired adhesion, and the "grafting to", a novel DOMA-SBMA copolymer with adhesion and wettability is developed for constructing a bacteriostatic surface. Specifically, the antibacterial coating is prepared via free radical polymerization and grafting to methods on the surface of stainless steel, and characterized by SCA, FTIR, XPS, SEM, and AFM to confirm the modification process. Antibacterial activity evaluation using <i>Staphylococcus aureus</i> (<i>S. aureus</i>) and <i>Escherichia coli</i> (<i>E. coli</i>) shows that the coating presents satisfactory antibacterial performance. The results showed that DOMA-SBMA coating is enough for antibacterial application, with high antibacterial efficiency against <i>E. coli</i> (92.2%) and <i>S. aureus</i> (95.0%). In summary, the bioinspired coating developed here may improve the stability of zwitterionic coatings and provides a simple preparation strategy for constructing antibacterial coatings.