The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: a large sample OSA study with 34-second and 52-second cut-off values was established
The study first quantifies the dose-response relationship between LAD and LSaO<sub>2</sub> and establishes relevant clinical thresholds. The developed model can accurately identify patients at risk of severe and moderate-severe hypoxia, offering a new tool for individualized intervention.
Authors
- Simin Gao
- Lei Li (ORCID: https://orcid.org/0000-0001-8723-3461)
- Xiaobo Zhou
- Ping Zeng
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fphys.2025.1691994
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00