Bidirectional Regulation between Metabolic Dysfunction-associated Steatotic Liver Disease and Sarcopenia via Liver-muscle Crosstalk
Our findings suggest a potential bidirectional causal relationship between MASLD and sarcopenia, which may be partially mediated by C-C motif chemokine ligand 2 and adrenomedullin.
Authors
- ZIXUAN WANG
- Jian-Gao Fan
- Cen Xie
- Youjie Zheng
- Yameng Liu
- Jie Jiang
- Yeyu Song (ORCID: https://orcid.org/0009-0001-5070-2030)
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Sciences (CN)
- XinHua Hospital (CN)
- Shanghai Institute of Nutrition and Health (CN)
- Shanghai Institute of Materia Medica (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.14218/jcth.2025.00538
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00