Multi-omics analysis identifies mitochondrial dysfunction in CD83+ macrophages as a key event in diabetic peripheral neuropathy progression

This study highlights the first discovery of CD83+ macrophages in DPN progression and identifies TIMM23 as a potential diagnostic and therapeutic marker.

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Publication Details

Journal
Neurobiology of Disease
Published
2026-01-07
DOI
https://doi.org/10.1016/j.nbd.2026.107262
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Multi-omics analysis identifies mitochondrial dysfunction in CD83+ macrophages as a key event in diabetic peripheral neuropathy progression

Yumin Lin, Yang Shen, Jiahua Wu, Hanbing Zhao et al.
Neurobiology of Disease
Pain Mechanisms and Treatments
article

Multi-omics analysis identifies mitochondrial dysfunction in CD83+ macrophages as a key event in diabetic peripheral neuropathy progression

Yumin Lin, Yang Shen, Jiahua Wu, Hanbing Zhao, Yucheng Wang, Caixia Yao, Jiale Lin, Jianbo Li, Yucong Chen, Hongman Zhang, Yijin Zhao
article en

Abstract

This study highlights the first discovery of CD83+ macrophages in DPN progression and identifies TIMM23 as a potential diagnostic and therapeutic marker.

Neurobiology of DiseaseVol. 219
The First People's Hospital of Shunde (CN), Community Health Center (US), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 95%
Pain Mechanisms and Treatments
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