Chronic intermittent hypoxia exacerbates isoproterenol-induced cardiac hypertrophy and apoptosis
CIH exhibits a negative effect on ISO-treated mice and cells, leading to an exacerbation of cardiac dysfunction and remodeling. In addition, CIH aggravates ISO-treated cardiomyocyte apoptosis in H9C2 cells.
Authors
- Ming Zhang (ORCID: https://orcid.org/0000-0003-2909-8446)
- Hanqiao Jiang (ORCID: https://orcid.org/0009-0008-5936-4550)
- Yujie Zhang
- Fang Fang
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Health and Family Planning Commission (CN)
- Beijing Anzhen Hospital (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fcvm.2025.1700967
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China