Mafu Yishen Formula ameliorates membranous nephropathy by promotion of regulatory T cell differentiation: a multi-omics study
MFYS modulates the immune response in PHN rats, reduces IgG deposition, and ameliorates renal and podocyte injury. It promotes Treg differentiation, regulates the cytokine network, and exerts multi-target effects on both inflammation and metabolism.
Authors
- Yuehong Hu
- Qihan Zhao (ORCID: https://orcid.org/0000-0003-4381-0591)
- Yanyu Cui
- Haoran Dai
- N. Zhang
- Hanxue Jiang
- Qian Ding
- Baoli Liu
- Hongliang Rui
- Shuxian Huang
- Wu Liu
- Gen Li
- Xiaoyu Cui
- Yang Zheng
- Yalin Zheng
- Yangzi Chen
- Xinyue Tang
Institutions
- Beijing University of Chinese Medicine (CN)
- Capital Medical University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1186/s13020-025-01272-1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00