Sodium-Glucose Cotransporter-2 Inhibitors and Acute Kidney Injury Risk: A Systematic Review and Meta-Analysis of Randomized Trials
SGLT2is conferred substantial renoprotective benefits but increases the risk of certain nonrenal AEs. Tailored treatment and close monitoring are crucial to ensure safety and efficacy, especially in high-risk patients.
Authors
- Yu-Cheng Chiang
- Yi‐Wen Chiu (ORCID: https://orcid.org/0000-0001-6840-5440)
- Hugo Y.-H. Lin
- Dao-Fu Dai
Institutions
- Johns Hopkins University (US)
- Kaohsiung Medical University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Cathay General Hospital (TW)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1016/j.xkme.2026.101248
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00