Lipoic Acid Ameliorates Lipopolysaccharide‐Induced Inflammation via Inhibition of Glycolysis in RAW264.7 Macrophages
LA exerts potent anti-inflammatory effects by targeting HIF1α-mediated metabolic reprogramming in macrophages. Our results highlight the therapeutic potential of targeting immunometabolic pathways in inflammatory lung diseases, providing new insights into the mechanism by which LA ameliorates pulmonary inflammation.
Authors
- R. Wang (ORCID: https://orcid.org/0000-0002-5059-8456)
- Liduo Yue (ORCID: https://orcid.org/0000-0002-7184-9170)
- Kai Wang (ORCID: https://orcid.org/0000-0002-7054-704X)
- Lihong Fan
- Linbei Lu
Institutions
- Shanghai Tenth People's Hospital (CN)
- Shanghai Sixth People's Hospital (CN)
- Shanghai Sunshine Rehabilitation Center (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1002/iid3.70313
- Primary Topic
- Biochemical Acid Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00