Prolonged survival in a young Dobermann with adrenal neuroblastoma

Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry. Adrenal neuroblastomas are extremely uncommon and this dog represents one of the few documented cases. The patient remained asymptomatic (except for diarrhoea episodes) for 18 months following surgery, which is an unusually prolonged survival for this aggressive neoplasm, but was euthanased due to rapid deterioration caused by multiple metastases of the neuroblastoma. This case highlights the diagnostic and therapeutic challenges of rare adrenal tumours in veterinary medicine.

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Publication Details

Journal
Veterinary Record Case Reports
Published
2026-01-08
DOI
https://doi.org/10.1002/vrc2.70330
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Prolonged survival in a young Dobermann with adrenal neuroblastoma

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Veterinary Record Case Reports
Neuroblastoma Research and Treatments
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Prolonged survival in a young Dobermann with adrenal neuroblastoma

Tamara Weitzer, Johannes Hirschberger, Ralf S. Mueller, Sara Soto, Ivan Stoikov, Irina Abramenko, Nataliia Ignatenko, Galyna Mazurkevych, Dmytro Litvinenko
article en

Abstract

Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry. Adrenal neuroblastomas are extremely uncommon and this dog represents one of the few documented cases. The patient remained asymptomatic (except for diarrhoea episodes) for 18 months following surgery, which is an unusually prolonged survival for this aggressive neoplasm, but was euthanased due to rapid deterioration caused by multiple metastases of the neuroblastoma. This case highlights the diagnostic and therapeutic challenges of rare adrenal tumours in veterinary medicine.

Veterinary Record Case ReportsVol. 14(1)
University of Bern (CH), West Health (US), Département Santé Animale (FR), Japan Small Animal Medical Center (JP), Kyiv City Clinical Oncology Center (UA)
Good health and well-being
Openalex Percentile: Top 93%
Neuroblastoma Research and Treatments
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