Impact of posthemorrhagic ventricular dilatation on cerebral oxygenation in preterm infants with intraventricular hemorrhage

Cerebral oxygenation declines with increasing intraventricular hemorrhage (IVH) severity in preterm infants. Posthemorrhagic ventricular dilatation (PHVD) severity, reflected by the number of neurosurgical interventions, is linked to worsening cerebral oxygenation and increased oxygen extraction. This prospective cohort study provides a comprehensive longitudinal dataset using near-infrared spectroscopy (NIRS) to link IVH severity and PHVD to cerebral oxygenation dynamics. Findings underscore the urgent need for targeted neuroprotective interventions to stabilize brain oxygenation in preterm infants with severe IVH and PHVD.