One-pot synthesis of ynamines from employing multicomponent reaction of isothiocyanate

An efficient one-pot synthesis of functionalized ynamines is described. This involves the multicomponent reaction of ammonium thiocyanate, benzoy chlorides, and secondary amines in the presence of dialkylacetylenedicarboxylates in acetone at reflux conditions.

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Publication Details

Published
2025-03-28
DOI
https://doi.org/10.82361/iranjoc.2025.1202875
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
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article

One-pot synthesis of ynamines from employing multicomponent reaction of isothiocyanate

IAU
Sulfur-Based Synthesis Techniques
article

One-pot synthesis of ynamines from employing multicomponent reaction of isothiocyanate

IAU
article en

Abstract

An efficient one-pot synthesis of functionalized ynamines is described. This involves the multicomponent reaction of ammonium thiocyanate, benzoy chlorides, and secondary amines in the presence of dialkylacetylenedicarboxylates in acetone at reflux conditions.

Clean water and sanitation
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Sulfur-Based Synthesis Techniques
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One-pot synthesis of ynamines from employing multicomponent reaction of isothiocyanate — IAU · (2025) | TGRS Research Map | TGRS