A bortezomib resistance–related gene signature predicts prognosis, with ARID5B downregulation associated with poor overall survival in multiple myeloma

The BRGs signature is a reliable biomarker for predicting the prognosis of MM and helps optimize clinical decision-making for treatment, and identifies key gene ARID5B downregulation as an adverse prognostic factor in multiple myeloma.

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Publication Details

Journal
Discover Oncology
Published
2026-01-06
DOI
https://doi.org/10.1007/s12672-026-04383-9
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

A bortezomib resistance–related gene signature predicts prognosis, with ARID5B downregulation associated with poor overall survival in multiple myeloma

Meng Xiao, Jiajia Wang, Xiong Shudao, Xunyi Jiao et al.
Discover Oncology
Chromatin Remodeling and Cancer
article

A bortezomib resistance–related gene signature predicts prognosis, with ARID5B downregulation associated with poor overall survival in multiple myeloma

Meng Xiao, Jiajia Wang, Xiong Shudao, Xunyi Jiao, Jinjing Guo, Jinli Zhu, Yangyang Ding
article en

Abstract

The BRGs signature is a reliable biomarker for predicting the prognosis of MM and helps optimize clinical decision-making for treatment, and identifies key gene ARID5B downregulation as an adverse prognostic factor in multiple myeloma.

Discover OncologyVol. 17(1)
Fuyang Normal University (CN), Anhui Medical University (CN), Zhongda Hospital Southeast University (CN), The People's Hospital Tongling (CN), Jining First People's Hospital (CN), Second Affiliated Hospital of Anhui Medical University (CN)
Openalex Percentile: Top 94%
Chromatin Remodeling and Cancer
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