Fibroepithelioma of Pinkus on the Plantar Foot: A Rare Case

Fibroepithelioma of Pinkus (FEP) is an uncommon histologic variant of basal cell carcinoma that classically arises on the trunk and proximal extremities. We present the case of a 59-year-old Hispanic man with a 15-year history of a slowly enlarging, intermittently painful nodule on the left plantar foot. Clinical examination revealed a pearly, telangiectatic, hyperkeratotic nodule, and biopsy demonstrated anastomosing cords of basaloid cells within a fibromyxoid stroma, consistent with FEP. This case highlights an atypical acral presentation of FEP and contributes to the limited literature documenting its occurrence on the plantar foot. Recognition of this rare variant in unusual anatomic locations is important, because persistent acral lesions may seem clinically benign yet require timely biopsy to ensure accurate diagnosis and appropriate surgical management.

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Publication Details

Journal
American Journal of Dermatopathology
Published
2026-01-06
DOI
https://doi.org/10.1097/dad.0000000000003210
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Fibroepithelioma of Pinkus on the Plantar Foot: A Rare Case

Aashni Bhukhan, Fahad Siddiqui, Summer Wong, Patrick Dominguez
American Journal of Dermatopathology
Nonmelanoma Skin Cancer Studies
article

Fibroepithelioma of Pinkus on the Plantar Foot: A Rare Case

Aashni Bhukhan, Fahad Siddiqui, Summer Wong, Patrick Dominguez
article en

Abstract

Fibroepithelioma of Pinkus (FEP) is an uncommon histologic variant of basal cell carcinoma that classically arises on the trunk and proximal extremities. We present the case of a 59-year-old Hispanic man with a 15-year history of a slowly enlarging, intermittently painful nodule on the left plantar foot. Clinical examination revealed a pearly, telangiectatic, hyperkeratotic nodule, and biopsy demonstrated anastomosing cords of basaloid cells within a fibromyxoid stroma, consistent with FEP. This case highlights an atypical acral presentation of FEP and contributes to the limited literature documenting its occurrence on the plantar foot. Recognition of this rare variant in unusual anatomic locations is important, because persistent acral lesions may seem clinically benign yet require timely biopsy to ensure accurate diagnosis and appropriate surgical management.

American Journal of Dermatopathology
Memorial Regional Hospital (US)
Openalex Percentile: Top 95%
Nonmelanoma Skin Cancer Studies
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