Motor, not cognitive, performance relates to amyloid status in normal older adults
The National Institutes of Health ToolBox motor performance may signal early Alzheimer's disease (AD) risk, even before memory change.Balance performance may be sensitive to early cumulative AD-neuropathology loading.Motor measures should be included in early AD-risk detection batteries.
Authors
- Bruno Giordani (ORCID: https://orcid.org/0000-0001-5921-3455)
- Amanda Cook Maher (ORCID: https://orcid.org/0000-0001-6229-4743)
- Kelly N DuBois (ORCID: https://orcid.org/0000-0002-1349-1983)
- Savannah G. Rose (ORCID: https://orcid.org/0000-0001-9784-6819)
- Nicholas M. Kanaan (ORCID: https://orcid.org/0000-0002-4362-2593)
- Emma Flynn (ORCID: https://orcid.org/0000-0002-2340-4273)
- Carol Persad
- Robert A. Koeppe
- Jordan Bross
- Yi Lu Murphey
Institutions
- Grand Rapids Community College (US)
- University of Michigan (US)
- University of Michigan–Dearborn (US)
- Michigan State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1002/dad2.70237
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Michigan State University
- College of Engineering, Michigan State University
- National Institute on Aging