Gut virome dysbiosis contributes to premature ovarian insufficiency by modulating gut bacteriome
Our findings demonstrate the critical roles of the gut virome in regulating ovarian function and provide new insights into the pathogenesis of POI. This study also underscores the therapeutic potential of the gut virome in improving ovarian dysfunction and female infertility including POI.
Authors
- J L Jin (ORCID: https://orcid.org/0009-0000-0131-9791)
- Guixiang Yao
- T X Zhang
- QunYe Zhang
- Yongze Yu (ORCID: https://orcid.org/0000-0003-2324-3606)
- Ye Bi (ORCID: https://orcid.org/0000-0002-6626-3589)
- Yating Zhao (ORCID: https://orcid.org/0009-0004-3809-082X)
- Xinjie Zhang (ORCID: https://orcid.org/0009-0006-0476-1933)
- Hengbo Ye
- Zihan Qin
- Xiaoming Zhou
- Xiaoyu Ren
- Zhe Wang
- Haiyan Chen
- Xiaowei Wang
- Yun Zhang
Institutions
- Wenzhou Medical University (CN)
- Jinan Central Hospital (CN)
- Taiyuan Maternity and Child Care Hospital (CN)
- Shandong Provincial Hospital (CN)
- Dongyang People's Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
- University College London (GB)
Publication Details
- Journal
- Gut Microbes
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1080/19490976.2025.2611645
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 31.91