Beyond the Matrix: A Rare Case of Pilomatrix Carcinoma with Histologic Insights

Pilomatrix carcinoma is rare entity which arises from matrical cells of hair follicle and misdiagnosed quite often. A 27 years female with presented with a swelling on right side of nape of neck for approximately 3 years which was painless, slowly progressive, soft to firm in consistency. Previously misdiagnosed as squamous cell carcinoma, the lesion recurred and was excised again in our institution and was diagnosed here as Pilomatrix carcinoma with regional lymph node metastasis. Since she had metastasis, the patient is currently undergoing radiotherapy. Considering the rarity of this carcinoma it was noteworthy to report this case as correct diagnosis aids patient’s treatment protocol and improves prognosis.

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Publication Details

Journal
Annals of Pathology and Laboratory Medicine
Published
2026-01-05
DOI
https://doi.org/10.21276/apalm.3745
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00

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article

Beyond the Matrix: A Rare Case of Pilomatrix Carcinoma with Histologic Insights

Prima Shuchita Lakra, Rahul Kumar Bharti, Sanjeet Kumar Singh, Monalisa Katyare et al.
Annals of Pathology and Laboratory Medicine
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article

Beyond the Matrix: A Rare Case of Pilomatrix Carcinoma with Histologic Insights

Prima Shuchita Lakra, Rahul Kumar Bharti, Sanjeet Kumar Singh, Monalisa Katyare, Amiy Arnav, Nidhi Priya Barla
article en

Abstract

Pilomatrix carcinoma is rare entity which arises from matrical cells of hair follicle and misdiagnosed quite often. A 27 years female with presented with a swelling on right side of nape of neck for approximately 3 years which was painless, slowly progressive, soft to firm in consistency. Previously misdiagnosed as squamous cell carcinoma, the lesion recurred and was excised again in our institution and was diagnosed here as Pilomatrix carcinoma with regional lymph node metastasis. Since she had metastasis, the patient is currently undergoing radiotherapy. Considering the rarity of this carcinoma it was noteworthy to report this case as correct diagnosis aids patient’s treatment protocol and improves prognosis.

Annals of Pathology and Laboratory MedicineVol. 13(1)
All India Institute of Medical Sciences, Deoghar (IN)
All-India Institute of Medical Sciences
Good health and well-being
Openalex Percentile: Top 95%
Cancer and Skin Lesions
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