HLA‐DR Matching in Kidney Transplantation: Ethnic Disparities in Clinical Benefit and Policy Implications From a UK Registry Analysis

HLA-DR matching improves graft survival overall but offers limited benefit in Black recipients, likely due to low-resolution typing inadequately capturing immunological compatibility across ethnic lines. The current UK-KAS scoring system may inadvertently disadvantage ethnic minorities by delaying transplantation for matches that confer minimal benefit. Our findings support incorporating ethnicity-specific considerations into kidney allocation policy to promote equity and optimize outcomes.