Evaluation of Anti-Inflammatory and Wound-Healing Activities of Triphala: A Phytochemical and Extraction-Based Study of a Classical Ayurvedic Formulation

Triphala, a classical Ayurvedic formulation composed of Amalaki, Haritaki, and Bibhitaki, is traditionally recognized for its Shothahara (anti-inflammatory) and Vranaropana (wound-healing) properties. The present study scientifically evaluates these activities using carrageenan-induced paw edema and excision wound models in Wistar rats. The ethanolic extract of Triphala demonstrated significant suppression of acute inflammation and significantly enhanced wound contraction and epithelialisation. These effects may be attributed to the presence of tannins, flavonoids, and phenolic compounds that support tissue repair, collagen formation, and antimicrobial action. The findings substantiate the classical Ayurvedic claims regarding the therapeutic potential of Triphala.