Navigating prognostic stratification and approach to TP53-mutated myeloid neoplasms
This review highlights the current understanding of TP53 -MT MN, evolving strategies of prognostic stratification and propose a practical framework for clinical management. We further discuss the critical unmet need for collaborative, biologically informed clinical trials to improve outcomes of this challenging disease entity.
Authors
- Talha Badar (ORCID: https://orcid.org/0000-0003-1548-918X)
- Naseema Gangat
- Ayalew Tefferi
Institutions
- Mayo Clinic (US)
- WinnMed (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Current Opinion in Hematology
- Published
- 2025-12-29
- DOI
- https://doi.org/10.1097/moh.0000000000000906
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77