Humoral and cellular immunogenicity of COVID-19 vaccine boosters in participants with advanced HIV disease
COVID-19 vaccine boosters enhance immunity in PLWH, however, the responses remain suboptimal compared to immunocompetent individuals, emphasising the need for tailored vaccination strategies.
Authors
- Khanyisile Tshabalala (ORCID: https://orcid.org/0000-0002-6018-7212)
- Mieke A. van der Mescht (ORCID: https://orcid.org/0000-0002-7521-1756)
- Ishen Seocharan (ORCID: https://orcid.org/0000-0002-5547-2393)
- Helen C. Steel (ORCID: https://orcid.org/0000-0001-5899-4472)
- Nevilene Slingers (ORCID: https://orcid.org/0000-0002-1670-1755)
- Thanusha Pillay
- Simone I. Richardson (ORCID: https://orcid.org/0000-0001-7678-2609)
- Thandeka Moyo-Gwete (ORCID: https://orcid.org/0000-0002-4269-9281)
- Lee-Ann Crystal Davids (ORCID: https://orcid.org/0000-0001-7596-1402)
- Veronica Ueckermann (ORCID: https://orcid.org/0000-0002-4419-3583)
- Prudence Kgagudi
- Theresa M. Rossouw (ORCID: https://orcid.org/0000-0003-4066-922X)
- Nelia P. Manamela (ORCID: https://orcid.org/0000-0002-2792-4815)
- Carol Crowther (ORCID: https://orcid.org/0000-0002-0287-7004)
- Penny L. Moore (ORCID: https://orcid.org/0000-0001-8719-4028)
- Dexter Chiveto
- Tarylee Reddy
- Rofhiwa Nesamar
- Nomcebo Shusha
- Fareed Abdullah
Institutions
- National Health Laboratory Service (ZA)
- South African Medical Research Council (ZA)
- University of the Witwatersrand (ZA)
- University of Pretoria (ZA)
Publication Details
- Journal
- Journal of Infection
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1016/j.jinf.2026.106676
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- South African Medical Research Council
- Poliomyelitis Research Foundation
- University of Pretoria
- Medical Research Council