Assessment of N/L ratio and subclinical atherosclerosis in FH subjects with or without LDLR mutation
FH subjects with LDLR mutations had a higher NLR and a more severe atherosclerosis distribution. Our findings support the role of NLR as a noninvasive biomarker of early immune activation and highlights the importance of lipoinflammatory status evaluation in FH subjects.
Authors
- Nicoletta Miano (ORCID: https://orcid.org/0000-0003-0429-9807)
- Giosiana Bosco (ORCID: https://orcid.org/0009-0004-6036-927X)
- Maurizio Di Marco (ORCID: https://orcid.org/0000-0001-9021-6101)
- Salvatore Piro (ORCID: https://orcid.org/0000-0001-9838-5612)
- M. Papa (ORCID: https://orcid.org/0000-0002-2139-346X)
- Ernestina Marianna De Francesco (ORCID: https://orcid.org/0000-0002-2810-6128)
- Roberta Malaguarnera (ORCID: https://orcid.org/0000-0003-4149-9488)
- Ivan Privitera (ORCID: https://orcid.org/0000-0003-3687-0051)
- Giovanni Pennisi
- Francesco Barbagallo (ORCID: https://orcid.org/0009-0007-2746-8104)
- Marina Martedì
- Antonino Di Pino
- Francesca Valenza
- Roberto Scicali
- Chiara Piazza
- Sabrina Scilletta
Institutions
- Università degli Studi di Enna Kore (IT)
- University of Catania (IT)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1210/jendso/bvag001
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 30.93