Photodistributed Hyperpigmentation Associated With COVID-19 Vaccination

While the COVID-19 vaccine has been associated with a variety of cutaneous reactions, there is little evidence describing drug-induced hyperpigmentation after vaccination. Although we cannot definitively establish a causal relationship between the patient's COVID-19 vaccination and the development of her photoinduced hyperpigmentation, an in-office literature review suggested the correlation of these two events. The timing of the vaccine relative to the onset of pigmentary changes and the absence of other identifiable metabolic triggers elevate COVID-19 vaccination as a plausible offending agent. This report is intended to raise awareness of a rare but cosmetically disfiguring potential complication of COVID-19 vaccination. &nbsp.