SBP: Always peritonitis in decompensated cirrhosis? Case report and review of the literature

We report a case of a 56-year-old male with alcohol-associated liver cirrhosis presenting with septic and obstructive shock due to spontaneous bacterial peritonitis and pericarditis with tamponade. Imaging revealed ascites, pleural and pericardial effusion requiring drainage. Escherichia coli with identical resistance patterns was cultured from all drained fluids. Scintigraphy confirmed a peritoneal-pericardial connection. After initial treatment, fluid recurrences prompted evaluation for transjugular intrahepatic portosystemic shunt (TIPS) placement, which was unfortunately complicated by severe bleeding, ultimately leading to multi-organ failure and death. This case highlights the exceptional occurrence of pericardial effusion and spontaneous bacterial pericarditis as well as peritonitis as a complication of decompensated cirrhosis, with confirmed connection between the pericardium and the abdominal cavity by nuclear tracer study, as well as microbiological evidence. Based on an overview of all published cases management includes diuretics, paracentesis and in refractory cases, TIPS. Liver transplantation remains the definitive treatment.

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Publication Details

Journal
Acta Gastro Enterologica Belgica
Published
2025-12-29
DOI
https://doi.org/10.51821/88.4.14181
Primary Topic
Liver Disease and Transplantation
Type
article
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article

SBP: Always peritonitis in decompensated cirrhosis? Case report and review of the literature

Vera Hartman, Wilhelmus J. Kwanten, Thomas Vanwolleghem, Evi Van Dyck et al.
Acta Gastro Enterologica Belgica
Liver Disease and Transplantation
article

SBP: Always peritonitis in decompensated cirrhosis? Case report and review of the literature

Vera Hartman, Wilhelmus J. Kwanten, Thomas Vanwolleghem, Evi Van Dyck, Jolien Derdeyn, Toon Steinhauser, Karolien Dams, Th. Van der Zijden, Luisa Vonghia, B. Bracke, S Francque, Y Van Loocke
article en

Abstract

We report a case of a 56-year-old male with alcohol-associated liver cirrhosis presenting with septic and obstructive shock due to spontaneous bacterial peritonitis and pericarditis with tamponade. Imaging revealed ascites, pleural and pericardial effusion requiring drainage. Escherichia coli with identical resistance patterns was cultured from all drained fluids. Scintigraphy confirmed a peritoneal-pericardial connection. After initial treatment, fluid recurrences prompted evaluation for transjugular intrahepatic portosystemic shunt (TIPS) placement, which was unfortunately complicated by severe bleeding, ultimately leading to multi-organ failure and death. This case highlights the exceptional occurrence of pericardial effusion and spontaneous bacterial pericarditis as well as peritonitis as a complication of decompensated cirrhosis, with confirmed connection between the pericardium and the abdominal cavity by nuclear tracer study, as well as microbiological evidence. Based on an overview of all published cases management includes diuretics, paracentesis and in refractory cases, TIPS. Liver transplantation remains the definitive treatment.

Acta Gastro Enterologica BelgicaVol. 88(4)
AZ Klina (BE), Antwerp University Hospital (BE)
Good health and well-being
Openalex Percentile: Top 28%
Liver Disease and Transplantation
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SBP: Always peritonitis in decompensated cirrhosis? Case report and review of the literature — Vera Hartman, Wilhelmus J. Kwanten, et al. · Acta Gastro Enterologica Belgica (2025) | TGRS Research Map | TGRS