Paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation presenting as hydrocele in an older man: a case report

This case emphasizes the rarity and highlights the importance of clinicopathological features, diagnostic pitfalls, and prognostic implications considering PTDDLPS with rhabdomyosarcomatous differentiation, reinforces the oncologic importance of a high inguinal approach for suspected malignant paratesticular masses in older men. IHC and molecular analyses are crucial for an accurate diagnosis, particularly in tumors with heterologous elements that may mimic other sarcomas or germ cell tumors. Early recognition and multidisciplinary management optimize local control and surveillance planning.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2026-01-06
DOI
https://doi.org/10.1097/ms9.0000000000004664
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation presenting as hydrocele in an older man: a case report

Junn-Liang Chang, Kuang-Ting Liu, Yueh-ching Chang, Yu-Chieh Lin
Annals of Medicine and Surgery
Sarcoma Diagnosis and Treatment
article

Paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation presenting as hydrocele in an older man: a case report

Junn-Liang Chang, Kuang-Ting Liu, Yueh-ching Chang, Yu-Chieh Lin
article en

Abstract

This case emphasizes the rarity and highlights the importance of clinicopathological features, diagnostic pitfalls, and prognostic implications considering PTDDLPS with rhabdomyosarcomatous differentiation, reinforces the oncologic importance of a high inguinal approach for suspected malignant paratesticular masses in older men. IHC and molecular analyses are crucial for an accurate diagnosis, particularly in tumors with heterologous elements that may mimic other sarcomas or germ cell tumors. Early recognition and multidisciplinary management optimize local control and surveillance planning.

Annals of Medicine and SurgeryVol. 88(2)
Tri-Service General Hospital (TW), Hsin Sheng College of Medical Care and Management (TW), Ming Chuan University (TW), Taoyuan Armed Forces General Hospital (TW), National Defense Medical Center (TW)
Openalex Percentile: Top 95%
Sarcoma Diagnosis and Treatment
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Paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation presenting as hydrocele in an older man: a case report — Junn-Liang Chang, Kuang-Ting Liu, et al. · Annals of Medicine and Surgery (2026) | TGRS Research Map | TGRS