Micheliolide alleviates myocardial ischemia/reperfusion injury in rats via KEAP1/NRF2-mediated suppression of oxidative stress and inflammation

MCL regulates the KEAP1/NRF2 signaling pathway to reduce oxidative stress and inflammation, producing a cardioprotective effect in rats with acute myocardial infarction undergoing ischemia-reperfusion injury.

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Publication Details

Journal
Immunopharmacology and Immunotoxicology
Published
2026-01-02
DOI
https://doi.org/10.1080/08923973.2025.2610660
Primary Topic
Genomics, phytochemicals, and oxidative stress
Type
article
Field-Weighted Citation Impact
0.00
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article

Micheliolide alleviates myocardial ischemia/reperfusion injury in rats via KEAP1/NRF2-mediated suppression of oxidative stress and inflammation

JinZhu Yin, Zhaozheng Liu, Qu Jin
Immunopharmacology and Immunotoxicology
Genomics, phytochemicals, and oxidative stress
article

Micheliolide alleviates myocardial ischemia/reperfusion injury in rats via KEAP1/NRF2-mediated suppression of oxidative stress and inflammation

JinZhu Yin, Zhaozheng Liu, Qu Jin
article en

Abstract

MCL regulates the KEAP1/NRF2 signaling pathway to reduce oxidative stress and inflammation, producing a cardioprotective effect in rats with acute myocardial infarction undergoing ischemia-reperfusion injury.

Immunopharmacology and ImmunotoxicologyVol. 48(1)
Changchun University of Chinese Medicine (CN), The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 95%
Genomics, phytochemicals, and oxidative stress
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