Longitudinal SARS‐CoV‐2 Antibody Response in Healthcare Workers: Benefit of Prior Infection and Heterologous Boosting on Anti‐Spike IgG Immunity
Our findings underscore that both vaccine platforms and prior infections shape the magnitude and quality of the humoral immune response, highlighting the importance of considering priming strategy, booster design and hybrid immunity when optimising COVID-19 vaccination schedules for durable protection.
Authors
- Rhea Buttiens
- Thessa Laeremans (ORCID: https://orcid.org/0000-0003-0703-5663)
- Joeri L. Aerts (ORCID: https://orcid.org/0000-0002-9902-3696)
- Ellen Vancutsem (ORCID: https://orcid.org/0000-0003-3701-0889)
- Els Van Nedervelde (ORCID: https://orcid.org/0000-0002-3836-0517)
- Deborah De Geyter (ORCID: https://orcid.org/0000-0001-9706-8922)
- Diederik De Cock
- Sabine D. Allard
Institutions
- Vrije Universiteit Brussel (BE)
- Universitair Ziekenhuis Brussel (BE)
Publication Details
- Journal
- Influenza and Other Respiratory Viruses
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1111/irv.70202
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- Vrije Universiteit Brussel