Prenatal Adversities and Risk of Persistent Youth Psychopathology and Altered Cortical Thinning
Results of this cohort study show that multiple prenatal adversities were associated with altered developmental trajectories of psychopathology and cortical maturation into midadolescence. These findings highlight the importance of fetal programming to mental health across life course and the need for additional study of risk and resiliency-conferring factors in utero.
Authors
- Jacqueline A. Clauss (ORCID: https://orcid.org/0000-0002-0532-6726)
- Scott Evan Hadland (ORCID: https://orcid.org/0000-0003-3189-6199)
- Alysa E. Doyle (ORCID: https://orcid.org/0000-0002-8536-2697)
- Phil H. Lee (ORCID: https://orcid.org/0000-0003-1770-3100)
- Erin C. Dunn (ORCID: https://orcid.org/0000-0003-1413-3229)
- Joshua L. Roffman (ORCID: https://orcid.org/0000-0003-4073-532X)
- Harrison T. Reeder (ORCID: https://orcid.org/0000-0001-8813-9127)
- Sofía Álvarez Perdomo
- Jodi M. Gilman (ORCID: https://orcid.org/0000-0001-5180-6694)
- Dongmei Zhi (ORCID: https://orcid.org/0000-0001-6906-8650)
- Dylan Hughes (ORCID: https://orcid.org/0009-0003-3759-2417)
- Liam R. Arteaga
- Jing Sui
- A. Eden Evins
Institutions
- Harvard University (US)
- University of California, Los Angeles (US)
- Purdue University West Lafayette (US)
- Beijing Normal University (CN)
- Massachusetts General Hospital (US)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
Publication Details
- Journal
- JAMA Psychiatry
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1001/jamapsychiatry.2025.4080
- Citations
- 1
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 41.22