Investigation on the Use of Deep Eutectic Solvents in the Synthesis of Polyhydroxyurethanes

ABSTRACT This study explores the use of reline (choline chloride–urea combination), a deep eutectic solvent (DES), in the synthesis of polyhydroxyurethanes through step‐growth polymerization between a polycarbonate and a diamine. The performance of reline was compared to that of ZnCl 2 /urea DES and MeCN as a typical conventional solvent, demonstrating its superiority in both conversion efficiency (Conv. > 99%) and molar mass ( M n 10% higher than that obtained with the two other solvents) of the resulting polymer. The versatility of the method was evaluated by testing various bis‐cyclic carbonates and primary diamines, revealing differences in reactivity, number‐average molar mass, and glass transition temperature values of the obtained polymers. Finally, a representative reaction was successfully scaled up, demonstrating the practical applicability of the methodology, albeit with some challenges related to heat transfer.