Association of glucagon-like peptide-1 agonist therapy with postsurgical outcomes following multilevel correction for adult spinal deformity: a propensity score-matched analysis

The findings reveal a significant reduction in the rates of pseudoarthrosis, hardware failure, readmission, and mortality in patients treated with GLP-1As. These results align with the recent literature, pointing to a potential complementary therapy in ASD management. Further studies characterizing the mechanism by which GLP-1As affect postoperative spinal physiology are warranted to assess their utility in optimizing patient outcomes.

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Publication Details

Journal
Asian Spine Journal
Published
2026-01-06
DOI
https://doi.org/10.31616/asj.2025.0407
Primary Topic
Scoliosis diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of glucagon-like peptide-1 agonist therapy with postsurgical outcomes following multilevel correction for adult spinal deformity: a propensity score-matched analysis

C. D'Amico, Charles A Reitman, James P. Lawrence, Robert Ravinsky et al.
Asian Spine Journal
Scoliosis diagnosis and treatment
article

Association of glucagon-like peptide-1 agonist therapy with postsurgical outcomes following multilevel correction for adult spinal deformity: a propensity score-matched analysis

C. D'Amico, Charles A Reitman, James P. Lawrence, Robert Ravinsky, J. Silvestre, Robert J. Ferdon, Stephen Lewis, Christopher Nielsen, John Glaser, Benjamin Jacques
article en

Abstract

The findings reveal a significant reduction in the rates of pseudoarthrosis, hardware failure, readmission, and mortality in patients treated with GLP-1As. These results align with the recent literature, pointing to a potential complementary therapy in ASD management. Further studies characterizing the mechanism by which GLP-1As affect postoperative spinal physiology are warranted to assess their utility in optimizing patient outcomes.

Asian Spine Journal
Medical University of South Carolina (US), University of South Carolina (US), University of Toronto (CA)
Good health and well-being
Openalex Percentile: Top 95%
Scoliosis diagnosis and treatment
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