Association of glucagon-like peptide-1 agonist therapy with postsurgical outcomes following multilevel correction for adult spinal deformity: a propensity score-matched analysis
The findings reveal a significant reduction in the rates of pseudoarthrosis, hardware failure, readmission, and mortality in patients treated with GLP-1As. These results align with the recent literature, pointing to a potential complementary therapy in ASD management. Further studies characterizing the mechanism by which GLP-1As affect postoperative spinal physiology are warranted to assess their utility in optimizing patient outcomes.
Authors
- C. D'Amico
- Charles A Reitman
- James P. Lawrence (ORCID: https://orcid.org/0000-0002-2945-145X)
- Robert Ravinsky (ORCID: https://orcid.org/0000-0001-7364-143X)
- J. Silvestre
- Robert J. Ferdon (ORCID: https://orcid.org/0009-0008-1885-5812)
- Stephen Lewis
- Christopher Nielsen
- John Glaser
- Benjamin Jacques
Institutions
- Medical University of South Carolina (US)
- University of South Carolina (US)
- University of Toronto (CA)
Publication Details
- Journal
- Asian Spine Journal
- Published
- 2026-01-06
- DOI
- https://doi.org/10.31616/asj.2025.0407
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00