Preparation of spiropyridine derivatives using TiO2/Fe3O4@MWCNTs MNCs: Evaluation of biological activity

In this study a new and procedure was reported for the synthesis of TiO2/Fe3O4@MWCNTs MNCs as a new heterogeneous organometallic catalyst. The catalyst was employed for the preparation of spiropyrrole via the one-pot condensation reactions enaminone, isatin derivatives, electron-deficient acetylenic compounds and alkyl bromides in water at room temperature. Also, antioxidant property of some prepared compounds was investigated using diphenyl-picrylhydrazine (DPPH) radical trapping experiment. Presently, bacteria that is not destroied with drug have generated many problems in the performance of many transferable disease. For this reason, discovering appropriate and new procedures for the dealing with these pathogens are important and recent study have focused on the investigation of the antibacterial effects on the prepared compounds.