Neuropeptide TIP39 as a pluripotent brain molecule and its potential functions in postpartum depression

The multifunctional nature of TIP39, as evidenced by its roles in diverse physiological processes, opens up a promising avenue for further investigation. The investigation of TIP39's role in mood regulation and maternal behavior provides a possible rationale for its consideration as a therapeutic target for PPD. This review is a tentative step to bridge TIP39 and PPD symptoms, with the ultimate goal of providing a new sight for the remedy of this prevalent and often debilitating disorder.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-08
DOI
https://doi.org/10.3389/fendo.2025.1674213
Citations
1
Primary Topic
Mechanisms of cancer metastasis
Type
article
Field-Weighted Citation Impact
22.24

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article

Neuropeptide TIP39 as a pluripotent brain molecule and its potential functions in postpartum depression

Hongchi Liu, Qiuyi Tang, Silin Wang, Yanghui Wei et al.
1 citations
Frontiers in Endocrinology
Mechanisms of cancer metastasis
22.24
article

Neuropeptide TIP39 as a pluripotent brain molecule and its potential functions in postpartum depression

Hongchi Liu, Qiuyi Tang, Silin Wang, Yanghui Wei, Ning Liao, Zhengzhong Yang, Tianhao Liu, Rao Fu
article en
1 citations

Abstract

The multifunctional nature of TIP39, as evidenced by its roles in diverse physiological processes, opens up a promising avenue for further investigation. The investigation of TIP39's role in mood regulation and maternal behavior provides a possible rationale for its consideration as a therapeutic target for PPD. This review is a tentative step to bridge TIP39 and PPD symptoms, with the ultimate goal of providing a new sight for the remedy of this prevalent and often debilitating disorder.

Frontiers in EndocrinologyVol. 16
Sun Yat-sen University (CN), The Seventh Affiliated Hospital of Sun Yat-sen University (CN), Eighth Affiliated Hospital of Sun Yat-sen University
National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 3%
Mechanisms of cancer metastasis
22.24
DOIOpen Access PDFOpenAlex
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Neuropeptide TIP39 as a pluripotent brain molecule and its potential functions in postpartum depression — Hongchi Liu, Qiuyi Tang, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS