IncL plasmid-mediated dissemination of OXA-48 β-lactamase and <i>bla</i> CTX-M-15 gene amplification identified <i>via</i> long-read sequencing in carbapenem-resistant Enterobacterales
A 30% prevalence of intestinal carriage of ESBL-producing Enterobacterales and a 3.4% carriage prevalence of CRE were found. Long-read sequencing revealed IncL plasmid-mediated dissemination of OXA-48 β-lactamase and <i>bla</i> <sub>CTX-M-15</sub> gene amplification, demonstrating its added value for antimicrobial resistance monitoring.
Authors
- P. Kabelíková
- Pavel Dřevínek
- Marie Brajerova (ORCID: https://orcid.org/0000-0002-5737-7859)
- Marcela Krůtová (ORCID: https://orcid.org/0000-0002-4511-9430)
- Jan Tkadlec (ORCID: https://orcid.org/0000-0002-0892-924X)
- Barbora Dratvova
- Anezka Gryndlerova
- Suhanya Prasad
Institutions
- Charles University (CZ)
- University Hospital in Motol (CZ)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1093/jacamr/dlaf254
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00