Predictors of Severe Herpes Zoster: Contributions of Immunosenescence, Metabolic Risk, and Lifestyle Behaviors
These findings support a multifactorial model of HZ severity in southeastern Romania, shaped by age, lifestyle behaviors, hormonal status, and metabolic risk. While incidence patterns align with international data, the strong impact of modifiable factors on complication rates highlights the need for targeted prevention and individualized risk assessment. Results offer a regional perspective that may inform future multicenter investigations.
Authors
- Simona Claudia Stefan (ORCID: https://orcid.org/0009-0007-2659-2189)
- Fănică Bălănescu (ORCID: https://orcid.org/0000-0003-1949-4218)
- Madălina Nicoleta Matei (ORCID: https://orcid.org/0000-0001-8482-2260)
- Dana Tutunaru (ORCID: https://orcid.org/0000-0003-3403-472X)
- Caterina Dumitru (ORCID: https://orcid.org/0000-0001-8953-6538)
- E. Niculet
- Mariana Lupoae (ORCID: https://orcid.org/0000-0003-1852-4024)
- Alina Oana Dumitru
- Andreea Lupoae
- Aurel Nechita
- Alin Laurențiu Tatu
Institutions
- Clinical Emergency Hospital Bucharest (RO)
- "Dunarea de Jos" University of Galati (RO)
Publication Details
- Journal
- Diseases
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3390/diseases14010026
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00