Autonomous flow reaction optimization guided by NMR spectroscopy and advanced Bayesian optimization algorithms
A closed-loop workflow combining an efficient optimization algorithm, an automated reaction platform, and in-line analysis using benchtop NMR enables autonomous and high-efficiency reaction optimization.
Authors
- Jean-Philippe Krieger
Institutions
- Centre National de la Recherche Scientifique (FR)
- Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation (FR)
- Syngenta (Switzerland) (CH)
- Nantes Université (FR)
Publication Details
- Journal
- Reaction Chemistry & Engineering
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d5re00504c
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 0.00