Autoclaved Peanuts Exhibit Reduced Immunoglobulin E Binding and Improved Oral Tolerability
Autoclaving peanuts induces important chemical changes including fragmentation, leading to decreased peanut allergenicity and consequently increased tolerability. This has the potential for novel immunotherapeutic approaches with more favorable side effect profiles.
Authors
- Hana Chazbey
- Liane Beaudette
- Eisha Ahmed
- Abdulaziz S Alrafiaah
- Kurt Dejgaard (ORCID: https://orcid.org/0000-0002-4327-0057)
- Adnan M. Al Ali
- Bruce Mazer (ORCID: https://orcid.org/0000-0003-4018-1419)
- C Cohen
- Moshe Ben‐Shoshan (ORCID: https://orcid.org/0000-0001-9083-1518)
- Duncan Lejtenyi
- Albert M. Berghuis (ORCID: https://orcid.org/0000-0002-2663-025X)
- Carmen Li (ORCID: https://orcid.org/0000-0002-6135-2582)
- Thomas Eiwegger
- Christine McCusker (ORCID: https://orcid.org/0000-0003-2150-9159)
- Diana Toscano‐Rivero
- Danbing Ke
- Bertrand J. Jean‐Claude
- Wei Zhao
Institutions
- University of Toronto (CA)
- Majmaah University (SA)
- United Arab Emirates University (AE)
- Montreal Children's Hospital (CA)
- Hospital for Sick Children (CA)
- McGill University Health Centre (CA)
- Universitätsklinikum St. Pölten (AT)
- Karl Landsteiner University of Health Sciences (AT)
- McGill University (CA)
Publication Details
- Journal
- Allergy
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1111/all.70208
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00