Assessing the endothelium’s role in COVID-19 severity using the HUVEC model
These findings suggest that HUVEC serves as a promising biological sensor for detecting inflammatory responses in COVID-19 patients and shows the crucial role of the endothelium in sustaining the cytokine storm that contributes to patient severity and mortality.
Authors
- Cynara Gomes Barbosa
- Corynne Stéphanie Ahouéfa Adanho
- Hayna Malta Santos
- Vitor Fortuna
- Sânzio Silva Santana
- Sètondji Cocou Modeste Alexandre Yahouédéhou
- Thassila Nogueira Pitanga
- Jéssica Rebouças Silva
- Marilda Souza Goncalves
- Isa Menezes Lyra
- Valéria Matos Borges
Institutions
- Universidade Federal da Bahia (BR)
- Fundação de Amparo à Pesquisa do Estado da Bahia (BR)
- Universidade Católica do Salvador (BR)
- Complexo Hospitalar Universitário Professor Edgard Santos (BR)
- Instituto de Saúde (BR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1689772
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00