Network toxicology and multidimensional bioinformatics analysis reveal the shared mechanism of action of bisphenol A and phthalates in glioblastoma

This study elucidates the potential pathways through which BPA and phthalates contribute to GBM development via shared molecular mechanisms, offering a theoretical foundation for the identification of relevant diagnostic biomarkers and therapeutic targets.

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Publication Details

Journal
Ecotoxicology and Environmental Safety
Published
2026-01-01
DOI
https://doi.org/10.1016/j.ecoenv.2025.119650
Primary Topic
Effects and risks of endocrine disrupting chemicals
Type
article
Field-Weighted Citation Impact
0.00
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article

Network toxicology and multidimensional bioinformatics analysis reveal the shared mechanism of action of bisphenol A and phthalates in glioblastoma

Zhonghua Sun, Xiaodong Li, Luyao Ma, Zijie Xiong et al.
Ecotoxicology and Environmental Safety
Effects and risks of endocrine disrupting chemicals
article

Network toxicology and multidimensional bioinformatics analysis reveal the shared mechanism of action of bisphenol A and phthalates in glioblastoma

Zhonghua Sun, Xiaodong Li, Luyao Ma, Zijie Xiong, Wei Ye, Yinuo Chen, Wencai Wang, Zun Wang
article en

Abstract

This study elucidates the potential pathways through which BPA and phthalates contribute to GBM development via shared molecular mechanisms, offering a theoretical foundation for the identification of relevant diagnostic biomarkers and therapeutic targets.

Ecotoxicology and Environmental SafetyVol. 309
Harbin Medical University (CN), Juntendo University (JP), Second Affiliated Hospital of Harbin Medical University (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 95%
Effects and risks of endocrine disrupting chemicals
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