A pyfluor mediated deoxyfluorination of 4-hydroxymethyloxazoles to 4-fluoromethyloxazoles under mild reaction conditions

We disclose an approach for 4-fluoromethyloxazoles from 4-hydroxymethyloxazoles via deoxyfluorination by employing a combination of PyFluor and AgF under mild reaction conditions.

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Publication Details

Journal
New Journal of Chemistry
Published
2026-01-01
DOI
https://doi.org/10.1039/d5nj04715c
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00
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article

A pyfluor mediated deoxyfluorination of 4-hydroxymethyloxazoles to 4-fluoromethyloxazoles under mild reaction conditions

Ramesh Chintakunta, Sujeet Kumar, K. M. Kajol
New Journal of Chemistry
Fluorine in Organic Chemistry
article

A pyfluor mediated deoxyfluorination of 4-hydroxymethyloxazoles to 4-fluoromethyloxazoles under mild reaction conditions

Ramesh Chintakunta, Sujeet Kumar, K. M. Kajol
article en

Abstract

We disclose an approach for 4-fluoromethyloxazoles from 4-hydroxymethyloxazoles via deoxyfluorination by employing a combination of PyFluor and AgF under mild reaction conditions.

New Journal of ChemistryVol. 50(6)
Central Drug Research Institute (IN), Academy of Scientific and Innovative Research (IN)
Openalex Percentile: Top 95%
Fluorine in Organic Chemistry
DOISourceOpenAlex
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