Enzymatic and genetic evaluation of butyrylcholinesterase in male infertility

This is the first study linking BCHE variants and reduced BChE enzymatic activity with male infertility. These findings suggest BChE as a potential biomarker and therapeutic target for idiopathic infertility.

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Publication Details

Journal
F&S Science
Published
2026-01-01
DOI
https://doi.org/10.1016/j.xfss.2025.12.008
Primary Topic
Cholinesterase and Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Enzymatic and genetic evaluation of butyrylcholinesterase in male infertility

Syed M. Nurulain, Ammara Younas, Khulah Sadia, Rabia Habib et al.
F&S Science
Cholinesterase and Neurodegenerative Diseases
article

Enzymatic and genetic evaluation of butyrylcholinesterase in male infertility

Syed M. Nurulain, Ammara Younas, Khulah Sadia, Rabia Habib, Sabir Hussain, Syed Shah, Sajid Mehmood, Aleena Rafique, Maria Arshad, Mahnoor Atequite, Zuha Sarwar
article en

Abstract

This is the first study linking BCHE variants and reduced BChE enzymatic activity with male infertility. These findings suggest BChE as a potential biomarker and therapeutic target for idiopathic infertility.

F&S Science
University of Verona (IT), Kent State University (US), COMSATS University Islamabad (PK), Asian University (TH), Sir Syed University of Engineering and Technology (PK)
Openalex Percentile: Top 94%
Cholinesterase and Neurodegenerative Diseases
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