The split elbow sign in amyotrophic lateral sclerosis: A systematic review and meta-analysis
Current evidence does not support a consistent SE pattern in ALS. Methodological variability and small sample sizes limit the generalizability of available findings, indicating that the SE is unlikely to provide meaningful diagnostic utility in routine clinical practice.
Authors
- Nathan Pavey (ORCID: https://orcid.org/0000-0001-9636-4391)
- Marianthi Arnaoutoglou (ORCID: https://orcid.org/0000-0001-6476-2651)
- Vasiliki Poulidou (ORCID: https://orcid.org/0000-0002-0147-3948)
- Vasilios K. Kimiskidis
- Sotirios Papagiannopoulos
- Steve Vucic (ORCID: https://orcid.org/0000-0002-8323-873X)
- Alessandro Bombaci
- Vasilis-Spyridon Tseriotis
Institutions
- Concord Hospital (US)
- Aristotle University of Thessaloniki (GR)
- Concord Repatriation General Hospital (AU)
- AHEPA University Hospital (GR)
- Agios Pavlos General Hospital (GR)
- IRCCS Policlinico San Donato (IT)
- G. Papanikolaou General Hospital (GR)
Publication Details
- Journal
- Neurophysiologie Clinique
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1016/j.neucli.2025.103134
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00