Perivascular Diffusivity Suggests Dynamic and Modifiable Glymphatic Transit in Idiopathic Intracranial Hypertension
These data support the hypothesis that changes in glymphatic transit are likely a result rather than a cause of IIH, that radiographic indices of glymphatic transit may be leveraged diagnostically, and that ALPS-indices measuring perivascular diffusivity are likely a physiologically valid reflection of glymphatic transit in humans.
Authors
- Jeremy N. Ford
- Alexander Brook (ORCID: https://orcid.org/0000-0003-1098-6224)
- Marc A. Bouffard (ORCID: https://orcid.org/0000-0003-2353-0736)
- Donnella S. Comeau (ORCID: https://orcid.org/0009-0001-8696-3259)
- Bart K. Chwalisz (ORCID: https://orcid.org/0000-0001-9918-1742)
- Robert M. Mallery
- Mahsa Alborzi Avanaki (ORCID: https://orcid.org/0000-0003-1264-6522)
- K. Reinshagen
- David C. Alsop (ORCID: https://orcid.org/0000-0002-8206-1995)
- Olivia Grech (ORCID: https://orcid.org/0000-0001-5560-802X)
- Bardia Abbasi
- Narjes Jaafar
- Joseph F. Rizzo
- Yu-Ming Chang
Institutions
- Massachusetts Eye and Ear Infirmary (US)
Publication Details
- Journal
- Journal of Neuro-Ophthalmology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1097/wno.0000000000002434
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00