Peripheral and autonomic nervous system involvement in spinocerebellar ataxia type 3: unveiling an invisible burden
Clinical features of peripheral and autonomic nervous system degeneration are very common in SCA3, may already be observed in pre-ataxic individuals, and independently contribute to patient-reported disease burden and clinician-rated overall ataxia severity.
Authors
- Nens van Alfen (ORCID: https://orcid.org/0000-0001-7839-8125)
- Kristofoor E Leeuwenberg (ORCID: https://orcid.org/0000-0003-2204-308X)
- Roderick P. P. W. M. Maas
- Bart P. van de Warrenburg
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1007/s00415-025-13588-x
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00