miR-4787-3p and miR-581 as predictive biomarkers for fibrosis and prognosis in pancreatic cancer
The downregulation of miR-4787-3p and miR-581 is a hallmark of pancreatic cancer, closely associated with tumor fibrosis and poor prognosis. These miRNAs represent promising circulating and tissue biomarker candidates for diagnosing PC and evaluating its fibrotic burden, suggesting potential utility for early detection and personalized treatment strategies.
Authors
- X Wang
- Zhiyuan Chen (ORCID: https://orcid.org/0000-0002-6820-3678)
- Guanglong Hu (ORCID: https://orcid.org/0000-0001-6060-1826)
- Y. Zhang
- Meng Pan (ORCID: https://orcid.org/0000-0002-4380-2324)
- Peng Chen
- Chao Zhang
- Xiaolong Zeng
- Zhengchao Shen
Institutions
- Wannan Medical College (CN)
- Anhui Medical University (CN)
- Anhui Conch Design and Research Institute of Building Materials (China) (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Qujiang People's Hospital (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1007/s12672-026-04389-3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00