Metatranscriptomic Identification of Trubanaman Virus Sequences in Patient with Encephalitis, Australia

Using metatranscriptomics, we identified Trubanaman virus in cerebrospinal fluid from a severely immunocompromised man who died of encephalitis in Queensland, Australia. Virus sequences were related to orthobunyaviruses previously detected in mosquitoes in Australia. Testing for other causes yielded negative results, suggesting that Trubanaman virus was the cause of this fatal encephalitis case.

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Publication Details

Journal
Emerging infectious diseases
Published
2025-12-01
DOI
https://doi.org/10.3201/eid3112.251190
Primary Topic
Viral Infections and Vectors
Type
article
Field-Weighted Citation Impact
0.00
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article

Metatranscriptomic Identification of Trubanaman Virus Sequences in Patient with Encephalitis, Australia

John Woodford, Krispin Hajkowicz, Mary E. Petrone, Andrea S. Henden et al.
Emerging infectious diseases
Viral Infections and Vectors
article

Metatranscriptomic Identification of Trubanaman Virus Sequences in Patient with Encephalitis, Australia

John Woodford, Krispin Hajkowicz, Mary E. Petrone, Andrea S. Henden, Kym Lowry, Elango Pillai, Edward Charles Holmes, Patrick N. A. Harris
article en

Abstract

Using metatranscriptomics, we identified Trubanaman virus in cerebrospinal fluid from a severely immunocompromised man who died of encephalitis in Queensland, Australia. Virus sequences were related to orthobunyaviruses previously detected in mosquitoes in Australia. Testing for other causes yielded negative results, suggesting that Trubanaman virus was the cause of this fatal encephalitis case.

Emerging infectious diseasesVol. 31(12)
Good health and well-being
Openalex Percentile: Top 29%
Viral Infections and Vectors
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